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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
14.55
Human Site:
S1118
Identified Species:
26.67
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
S1118
E
L
S
N
K
R
H
S
L
V
Q
T
L
S
G
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
T1056
L
T
G
L
L
P
P
T
S
G
T
V
L
V
G
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
S1145
E
L
S
N
K
R
H
S
L
V
Q
T
L
S
G
Dog
Lupus familis
XP_537788
2395
264756
P1108
K
L
K
C
C
G
S
P
L
F
L
K
G
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
S1118
E
L
S
N
K
R
H
S
L
V
Q
T
L
S
G
Rat
Rattus norvegicus
Q9ESR9
2434
270910
S1118
E
L
S
N
K
R
H
S
L
V
Q
T
L
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
Q1019
N
V
K
A
E
M
Q
Q
M
V
L
D
V
D
L
Chicken
Gallus gallus
XP_422330
2276
256293
L1029
H
I
L
F
Y
S
Q
L
K
G
R
S
R
D
E
Frog
Xenopus laevis
NP_001089022
2363
267334
R1060
G
T
V
W
I
R
G
R
D
I
Q
T
H
M
D
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
M1021
S
E
M
E
Q
I
V
M
D
L
G
L
P
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
D457
S
I
G
A
L
V
V
D
H
I
R
T
S
A
D
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
L666
V
H
P
G
A
Y
G
L
P
R
P
W
Y
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
D634
L
G
V
C
P
Q
H
D
I
L
F
P
E
L
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
13.3
100
13.3
N.A.
100
100
N.A.
6.6
0
20
0
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
20
100
26.6
N.A.
100
100
N.A.
33.3
20
26.6
13.3
N.A.
N.A.
N.A.
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
8
0
0
0
0
0
0
0
0
16
0
% A
% Cys:
0
0
0
16
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
16
16
0
0
8
0
16
16
% D
% Glu:
31
8
0
8
8
0
0
0
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
8
0
0
8
0
% F
% Gly:
8
8
16
8
0
8
16
0
0
16
8
0
8
0
39
% G
% His:
8
8
0
0
0
0
39
0
8
0
0
0
8
8
0
% H
% Ile:
0
16
0
0
8
8
0
0
8
16
0
0
0
0
0
% I
% Lys:
8
0
16
0
31
0
0
0
8
0
0
8
0
0
8
% K
% Leu:
16
39
8
8
16
0
0
16
39
16
16
8
39
8
8
% L
% Met:
0
0
8
0
0
8
0
8
8
0
0
0
0
8
0
% M
% Asn:
8
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
8
8
8
8
0
8
8
8
0
8
% P
% Gln:
0
0
0
0
8
8
16
8
0
0
39
0
0
0
0
% Q
% Arg:
0
0
0
0
0
39
0
8
0
8
16
0
8
0
0
% R
% Ser:
16
0
31
0
0
8
8
31
8
0
0
8
8
31
0
% S
% Thr:
0
16
0
0
0
0
0
8
0
0
8
47
0
0
8
% T
% Val:
8
8
16
0
0
8
16
0
0
39
0
8
8
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _